Intellex Acquires Expert by Big Village

We're thrilled to announce that Intellex has acquired Expert by Big Village, effective March 22, 2024. This strategic move enhances our capabilities and strengthens our commitment to delivering exceptional solutions to our customers.

Stay tuned for more updates on how this acquisition will benefit our clients and experts.

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Expert Details

Translational Medicine and Biomarker Research in Cancer Drug Discovery

ID: 739333 California, USA

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Expert is a Scientist with 8+ years of extensive hands-on experience and deep understanding of cancer biology with focus on chromatin, RNA, epigenetics and gene expression regulation. She is a leader of multiple projects with interdisciplinary collaborators, driving conceptualization, execution, and in-depth analysis of ideas and experiments resulting in 9+ publications and 15+ conference presentations. Expert has laboratory management experience including personnel hiring, training, creating standard operational protocols and financial budgeting.

As a Translational Medicine Scientist in her current role, Expert is a biomarker lead, responsible for development and execution of biomarker strategy for clinical development. Additional expertise includes developing and implementing biomarker assays in preclinical models and clinical trials, evaluating new technologies as potential novel biomarker assay platforms, preclinical work for MoA studies, identifying and refining patient population, assembly of preclinical data packages and writing IND reports in support of IND submission, overseeing academic collaborations and CROs, and is an integral partner in multidisciplinary team of discovery, DMPK and in vivo pharmacology scientists.

• Mammalian primary, hTERT modified and cancer (suspension, adherent, 2D and 3D) cells and mESC culture experience
• Engineering of mammalian cell lines using siRNA, shRNA and CRISPR-Cas9 methods
• DNA& RNA manipulation (cloning, PCR, qPCR, RT-PCR, Gibson assembly, site directed mutagenesis, etc.)
• Polysome profiling and Ribo-seq, RNA-seq, Polysome-seq/TrIP-seq, ChIP, eCLIP
• Protein expression and isolation, protein-protein interactions (pull downs, immunoprecipitation, LC/MS, single cell mass cytometry), Flow cytometry & FACS
• Immunofluorescence, wide-field, confocal and super-resolution microscopes, high content and automated microscopy experience, image acquisition and analysis, IHC and proximity ligation assay
• Cell-based assays (viability, proliferation and death assays, fluorescence and luminescence-based assays)
• Performed statistical analysis on data sets using Excel, Fiji and Prism GraphPad, FlowJo
• Experience in managing multiple projects that involve close interactions with internal and external collaborators, strong interpersonal and communication skills, meticulous record keeping skills
• Exceptional data organizational and analytical skills, attention to details
• Experience in creating SOP, training team members on current safety regulatory guidelines and standard practices, mentoring students and research assistants
• Innovative, driven with positive "can-do" attitude and strong problem-solving skills


Year Degree Subject Institution
Year: 2018 Degree: PhD Subject: Cell and Developmental Biology Institution: Charles University in Prague
Year: 2013 Degree: MSc Subject: Molecular Biology Institution: Comenius University in Bratislava
Year: 2011 Degree: BS Subject: Biology Institution: Comenius University in Bratislava

Work History

Years Employer Title Department
Years: 2022 to Present Employer: Undisclosed Title: Translational Medicine Scientist Department: Translational Medicine
• Biomarker lead- development and execution of biomarker strategy for clinical development
• Develop and implement biomarker assays in preclinical models and clinical trials
• Evaluate new technologies as potential novel biomarker assay platforms
• Preclinical work for MoA studies, identifying and refining patient population
• Assemble preclinical data packages and write IND reports in support of IND submissions
• Oversee academic collaborations and CROs
• Integral partner in multidisciplinary team of discovery, DMPK and in vivo pharmacology scientists
Years Employer Title Department
Years: 2018 to 2022 Employer: Stanford University School of Medicine Title: Postdoctoral Scholar Department: Department of Pathology, Stanford Cancer Institute
• Led discovery of novel functions of chromatin remodeling complexes leading to potential targeted therapies and biomarker based patient stratification
• Started collaborations with multiple laboratories, and adapted the techniques to develop the project
• Implemented Polysome-seq methodology for wide use in the laboratory
• Engineered stable cell lines carrying cancer mutations subunits using CRISPR-Cas9
• Conceptualized, performed and analyzed cell-based assays to identify small molecules inhibiting various cellular processes to achieve potential targeted therapies

Career Accomplishments

Medical / Professional
Postdoctoral Training, Cancer Biology at Stanford University, School of Medicine (2018-2022)
Publications and Patents Summary
Publications: 11
Conference Presentations: 15

Fields of Expertise

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