Expert Details

RNAi, Proteomics, Functional Genomics, Gene Expression, Automated Image Analysis

ID: 730026 Massachusetts, USA

Expert. Expert's has 30 years of experience in the fields of developmental genetics, signal transduction and genomics. By developing, improving, and applying a number of genetic techniques (germline clones, FLP/FRT, Gal4/UAS, etc.), his group identified many key components of the Receptor Tyrosine Kinases, JAK/STAT, Wnt, Hedgehog and Notch signaling pathways. In recent years, his group established high-throughput genome-wide RNAi screens to systematically interrogate the entire Drosophila genome in various cell-based assays. In 2003 he created the Drosophila RNAi Screening Center at Employer to make this technology available to the community. Currently, his laboratory is applying large-scale RNAi and proteomic methods to obtain a global understanding to the structure of a number of signaling pathways and their cross-talks. In addition, he is studying the roles of signaling pathways in homeostasis and tissue remodeling in Drosophila muscles and gut stem cells. Expert. Expert has trained more than 80 students and postdoctoral fellows, with most of them currently holding academic positions.

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Education

Year	Degree	Subject	Institution
Year: 1983	Degree: PhD	Subject: Genetics	Institution: University of Paris

Work History

Years	Employer	Title	Department
Years: 1986 to Present	Employer: Undisclosed	Title: Professor	Department: Genetics
Responsibilities: Lab Head Professor of Genetics

Additional Experience

Expert Witness Experience
CONSULTING ACTIVITIES Novartis, 2003-2004. EnVivo Pharmaceuticals, Scientific Advisory Board, 2003-2005.

Training / Seminars
DISTINGUISHED LECTURES/ KEYNOTES Keynote: FASEB meeting. Protein Phosphatases,1994. Keynote: Developmental Biology meeting, 1994. Keynote: French Developmental Biology meeting, Marseille, 2001. Keynote: Ohio University, 2001.Keynote: Japanese Cell Biology meeting, Yokohama, 2002. Boehringer Ingelheim Lecture, IRCM Montreal, 2002. Keynote: Bone and Teeth GRC, 2003. Sloan Kettering, President Lecture, 2003. R. Williams Lecture (Penn), 2004. Richard Akeson Lecture (Cincinnati), 2004. UCSD, Distinguished Lecturer, 2004. Keynote: FASEB meeting on Growth Factor signaling, 2005. Keynote: Keystone meeting on Signaling Networks, 2006. Sterling Lecture, DFCI, 2006. Fox Chase, Distinguished Lecturer, 2008. NCI, Distinguished Lecturer, 2008. Keynote: Lorne Cancer conference, 2008. Keynote: Protein Phosphorylation, Salk, 2008. Keynote: Sheffield Symposium, 2008. Keynote: RNAi Summit Boston, 2009. Society of Fellows, Scripps 2009. Keynote: ICDB retreat, Star Institute Singapore, 2009. Keynote: Recomb 2010, Lisbon. Alma Howard Lecture, McGill, 2011. Keynote: Asian Drosophila meeting, Taiwan, 2011. Keynote: Annual 25th French Drosophila Conference, 2011. PANELS, COMMITTEES, SCIENTIFIC ADVISORY BOARDS Past: NSF.Review Panel. Biological Instrumentation and Resources, 1991-1992.NSF, Academic Research Infrastructure, 1992. NCI, NIH. Member Special Study Section, 1994 -1995.NINDS, NIH. AdHoc reviewer, 1997.NSF, Developmental Mechanisms Review Panel, 1993-1998. CNRS, Marseille, Scientific Review Committee, 1999. Drosophila Developmental Biology Meeting Committee. Drosophila Crete meeting committee, 1995-2008. CNRS review committee, Curie UMR-144, 2002. EMBL, Scientific Review Committee, 2003. MDCN-5, NIH. Study Section, 2003. HFSP Fellowship review committee, 2004-2007. ZRG1 FO5 NIH Fellowships Study Section, 2004-2006.Carnegie Institute, Scientific Review Committee, 2004. MGB, NIH. Study Section, 2005. Cell Biology Keystone Symposia Study Group, 2005. Scientific Review Group ZNS1 SRB, 2006. ZRG1 FO5 NIH Fellowships Study Section, 2004-2006. NSF SBIR Panel. 2007. GATC, NIH. Study Section, 2008. ERC reviewer, 2009. NIBS, Beijing - Scientific Advisory Board. 2007-2009. Employer Scientific advisory committee on siRNA technology, 2003-2010. Labex-France 2011. Damon Runyon Scientific Advisory Committee, 2007-2011. Current: U.S. Drosophila Stock Center Advisory Board, 1996-present. IGBMC, Strasbourg - Scientific Advisory Board, 2006-present. Max Planck Institute for Biology of Ageing (Cologne) - Scientific Advisory Board, 2011-2016.

Training / Seminars

DISTINGUISHED LECTURES/ KEYNOTES
Keynote: FASEB meeting. Protein Phosphatases,1994. Keynote: Developmental Biology meeting, 1994. Keynote: French Developmental Biology meeting, Marseille, 2001. Keynote: Ohio University, 2001.Keynote: Japanese Cell Biology meeting, Yokohama, 2002. Boehringer Ingelheim Lecture, IRCM Montreal, 2002. Keynote: Bone and Teeth GRC, 2003. Sloan Kettering, President Lecture, 2003. R. Williams Lecture (Penn), 2004. Richard Akeson Lecture (Cincinnati), 2004. UCSD, Distinguished Lecturer, 2004. Keynote: FASEB meeting on Growth Factor signaling, 2005. Keynote: Keystone meeting on Signaling Networks, 2006. Sterling Lecture, DFCI, 2006. Fox Chase, Distinguished Lecturer, 2008. NCI, Distinguished Lecturer, 2008. Keynote: Lorne Cancer conference, 2008. Keynote: Protein Phosphorylation, Salk, 2008. Keynote: Sheffield Symposium, 2008. Keynote: RNAi Summit Boston, 2009. Society of Fellows, Scripps 2009. Keynote: ICDB retreat, Star Institute Singapore, 2009. Keynote: Recomb 2010, Lisbon. Alma Howard Lecture, McGill, 2011. Keynote: Asian Drosophila meeting, Taiwan, 2011. Keynote: Annual 25th French Drosophila Conference, 2011.

PANELS, COMMITTEES, SCIENTIFIC ADVISORY BOARDS
Past: NSF.Review Panel. Biological Instrumentation and Resources, 1991-1992.NSF, Academic Research Infrastructure, 1992. NCI, NIH. Member Special Study Section, 1994 -1995.NINDS, NIH. AdHoc reviewer, 1997.NSF, Developmental Mechanisms Review Panel, 1993-1998. CNRS, Marseille, Scientific Review Committee, 1999. Drosophila Developmental Biology Meeting Committee. Drosophila Crete meeting committee, 1995-2008. CNRS review committee, Curie UMR-144, 2002. EMBL, Scientific Review Committee, 2003. MDCN-5, NIH. Study Section, 2003. HFSP Fellowship review committee, 2004-2007. ZRG1 FO5 NIH Fellowships Study Section, 2004-2006.Carnegie Institute, Scientific Review Committee, 2004. MGB, NIH. Study Section, 2005. Cell Biology Keystone Symposia Study Group, 2005. Scientific Review Group ZNS1 SRB, 2006. ZRG1 FO5 NIH Fellowships Study Section, 2004-2006. NSF SBIR Panel. 2007. GATC, NIH. Study Section, 2008. ERC reviewer, 2009. NIBS, Beijing - Scientific Advisory Board. 2007-2009. Employer Scientific advisory committee on siRNA technology, 2003-2010. Labex-France 2011. Damon Runyon Scientific Advisory Committee, 2007-2011. Current: U.S. Drosophila Stock Center Advisory Board, 1996-present. IGBMC, Strasbourg - Scientific Advisory Board, 2006-present. Max Planck Institute for Biology of Ageing (Cologne) - Scientific Advisory Board, 2011-2016.

Language Skills

Language	Proficiency
French
English

Fields of Expertise

computer imaging software, DNA microarray, genetics, genome, genomics, image analysis, image processing, protein, protein characterization, protein isolation, RNA interference