Neurology, Multiple Sclerosis, Demyelination, Remyelination, Virus Infection of the Nervous System
ID: 726483
Minnesota, USA
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Dr. is board certified by the American Board of Psychiatry and Neurology. He is a world expert in central nervous system diseases. He has published over 350 peer reviewed paper on the topic. He holds 14 patents for inventions on how to enhance remyelination in diseases like multiple sclerosis. He has been editor of a number of books on this topic. He serves on multiple editorial boards. His practice revolves around patients with CNS demyelination. He championed the use of plasmapheresis in acute attacks of mutliple sclerosis. He has a large basic science laboratory investigating ways to help understand the basic mechanisms of disease and injury.
His clinical practice interests include Multiple sclerosis, demyelinating disorders, neurovirology, neuroimmunology, autoimmune paraneoplastic diseases. His research activites include Viral persistence, central nervous system demyelination, remyelination, immunogenetics, virus-host interactions, experimental neuropathology, viral models of demyelination, neuroepidemiology of multiple sclerosis.
His expertise include investigating the role of neurotransmitters in spinal cord injuries, spinal cord compression in reference to metastatic epidural tumors, myasthenia gravis in children, central neurogenic hyperventilation in a patient with brainstem astrocytoma, a ultrastructural and biochemical study of gangliosidosis, demyelination and leukodystrophy, CNS of mice infected with lymphocytic choriomeningitis virus (LCMV), Theiler’s virus-induced encephalomyelitis, pituitary dwarfism, viral pathogenesis, neonatal infection with Daniels strain of Theiler’s murine encephalomyelitis virus, vasa nervorum in neropathy, viruses in beta cells of Langerhans Islets, infections associated with chemical manifestations of diabetes, gene mapping within the H-2D region for the susceptibility of Theiler’s virus, antibodies to immune-response gene products (Ia Antigens) for Theiler’s virus, virus-induced demyelination (treatment, causes and other factors).
He has experience with immune promotion of remyelination, the possible association with diabetes mellitus, autoimmune diseases, neoplastic disorders and head trauma with multiple sclerosis, Theiler’s virus-induced demyelination and remyelination, immunopathology, disability in multiple sclerosis, intravenous immunoglobulin therapy, rehabilitation utilization patterns, patterns of health care service utilization, Theiler’s murine encephalomyelitis virus induced demyelination in normal and mutant mice, advanced MRI studies, T cell functions in murine model of multiple sclerosis, immune promotion of remyelination, myelin repair, optimization of antibody enhanced remyelination, spontaneous remyelination, recombinant human monoclonal antibody for promoting myelin repair in MS, mechanism of axonal loss in MS, aspirin for the treatment of MS related fatigue, non-ambulatory impairment in benign MS and other similar studies funded by the National Institutes of Health and the National Multiple Sclerosis Society.
National Multiple Sclerosis Society - 8 years on the sceintific advisory committee - 4 years as chair of the reveiw committeeNational Institutes of Health - 8 years of scientific committees working with NINDS reviewing grantsFast Track - Organization focused on finding a cure for mutliple sclerosisFast Cures - advisor and consultant to review the status of research funding in multiple sclerosis