Expert Details
molecular modelling, QSAR, drug design, cytokine mimics, complex systems, nanotechnology, biomaterials, machine learning, AI, evolutionary methods
ID: 729856
Australia
He has published over 250 research papers (e.g. Chemical Reviews, Nature Materials, Angewandte Chemie, Proceedings of the National Academy of Science USA, Advanced Materials) and book chapters, almost 60 research and client reports, is an inventor on 25 patents. His current H-index is 39 and i10 index (number of papers with >10 citations) is 16. He is President of a chemical societies association, has several editorial board appointments on high impact journals. Expert is the recipient a diverse International awards and honors including the Herman Skolnik award from the American Chemical Society (informatics), the Adrien Albert award of the Royal Australian Chemical Institute (medicinal chemistry), the Royal Academy of Engineering (UK) Distinguished Fellowship (bioengineering), and the CRC for Polymers Chairman’s Award for Excellence in Commercialization (drug design). An important aspect of his research has involved dissecting the quantitative structure-activity method and rebuilding it with modern mathematical and artificial intelligence methods and adapting evolutionary methods to design of bio-active molecules and materials for diagnostics, therapeutics, and regeneration. Some of the technology arising from this was licensed to Bio-RAD Corporation. He was a foundation member the complex systems science group established and published seminal cited papers in this field. His most recent work involves modelling the interactions of materials with biology, particular the ability of materials surface chemistry, physicochemical properties and topographies to modulate cell attachment, proliferation and differentiation, and the design of small molecule and peptides to modulate protein-protein interactions as drug leads.
Education
| Year | Degree | Subject | Institution |
|---|---|---|---|
| Year: 1980 | Degree: PhD | Subject: Chemical physics | Institution: Monash University |
| Year: 1975 | Degree: BAppSci | Subject: Physics | Institution: RMIT |
| Year: 1973 | Degree: BSc | Subject: Chemistry and Chenical Engineering | Institution: Monash Yniversity |
Work History
| Years | Employer | Title | Department |
|---|---|---|---|
| Years: 2017 to Present | Employer: Undisclosed | Title: Professor | Department: Chemistry & Physics |
Responsibilities:Research into molecular basis of molecule and materials interactions with biology, translation of basic research to the market, fostering multidisciplinary and international collaborations |
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| Years | Employer | Title | Department |
| Years: 2015 to Present | Employer: Undisclosed | Title: Visiting Professor | Department: Pharmacy |
Responsibilities:Use of AI and machine learning to model properties of biomaterials and design materials with improve properties for therapeutic and regenerative medicine. Develop new mathematical descriptors for topographical biomaterials and complexity measures for additive manufactured objects |
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| Years | Employer | Title | Department |
| Years: 2019 to Present | Employer: Undisclosed | Title: Fellow | Department: Evolutionary robotics |
Responsibilities:Use of machine learning and evolutionary methods to exemplify multilevel evolution of robots where materials, components, morphology and controllers of robots are evolved together to optimise fitness for task and operational environment. |
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| Years | Employer | Title | Department |
| Years: 2003 to Present | Employer: Undisclosed | Title: Adjunct Professor | Department: Pharmacy |
Responsibilities:Research into molecular design of drugs and application of AI and machine learning the drug design and development, regenerative medicine and biomaterials. |
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| Years | Employer | Title | Department |
| Years: 1983 to 2012 | Employer: CSIRO Division of Molecular Science | Title: Senior Principal Research Scientist | Department: Materials Science and Engineering |
Responsibilities:Scientific research into drugs for blood cancers, benign corrosion inhibitors, biomaterials for implantable and indwelling medical devices, computational toxicology of nanomaterials, bioactive agents for agricultural, veterinary, and human health applications, use of machine learning and AI to probe materials-biology interactions |
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Government Experience
| Years | Agency | Role | Description |
|---|---|---|---|
| Years: 2010 to 2010 | Agency: NICNAS | Role: QSAR expert working group | Description: |
| Years: 2008 to 2008 | Agency: Australian Givernment | Role: Revision of chemistry research categories | Description: |
| Years: 1982 to 1983 | Agency: Defence | Role: Senior Research Scientist | Description: Scientific research |
International Experience
| Years | Country / Region | Summary |
|---|---|---|
| Years: 2009 to 2010 | Country / Region: North America | Summary: Newton Turner Fellowship for Exceptional Senior Scientists |
| Years: 1998 to 1998 | Country / Region: UK | Summary: Australian Academy of Science traveling fellowship to Oxford University |
| Years: 1988 to 1988 | Country / Region: Japan | Summary: Australian Academy of Science traveling fellowship to Kyoto University |
Career Accomplishments
| Associations / Societies |
|---|
| RACI, past Chairman of the Board AFMC, past President STA, Board Member |
| Licenses / Certifications |
|---|
| FRACI, FAFMC, CChem, CPChem |
| Professional Appointments |
|---|
| Editorial Boards of ChemMedChem and BMC Buophysics Hon. Gen Secretary RACI Board Federation of Asian Chemical Societies Association of Molecular Modellers of Australia Science & Technology Australia, Ordinary member of STA Executive. Member of NH&MRC Career Development Fellowship Panel Member of management committee for COST Action MODENA (computational nanotoxicology) Member of IUPAC (International Union of Pure and Applied Chemistry) expert working group on nomenclature for computational drug design Member of NICNAS Working Group on Industrial Chemicals (Notification and Assessment) legislation Member, Australian Academy of Science, National Committee for Chemistry Member of NICNAS Human Health Expert Working Group (HHEWG) on QSAR Science and Technology Australia (STA) Board (Chemistry Cluster representative) Member: UIPAC Update of Glossary Terms used in Computational Drug Design Asian Federation for Medicinal Chemistry Coordinated revision of Chemical Science for the ABS new Australian Standard Research Classification (ASRC) Malvern Memorial Grammar School Board Australian representative on international planning committee, Pacifichem congress. CSIRO Complex Systems Science emerging science area (now CSIRO Complex Systems Science Theme) Adjunct Professor, Monash University; Australian representative Molecular Graphics and Modelling Society committee Board of Royal Australian Chemical Institute (RACI) Australian representative on the executive of the Asian Federation for Medicinal Chemistry Board member, International QSAR and Modelling Society Medicinal Chemistry Project (UNESCO/FACS) Reference group, Victorian Complementary and Alternative Medicine Research Centre, Alfred Hospital Trustee, Chemical Structure Association Trust Asian Federation for Medicinal Chemistry RACI Division of Biomolecular Chemistry (previously Medicinal and Agricultural Chemistry) DISR Delegate to Australia-Malaysia Bilateral Biotechnology Workshop & Senior Officials Meeting, Kuala Lumpur. Asian Chemical Information Network (UNESCO/FACS) Foundation Member, Molecular Design Society Committee member, RACI Medicinal & Agricultural Chemistry Division Secretary, RACI Division of Medicinal & Agricultural Chemistry Foundation Treasurer, RACI Medicinal and Agricultural Chemistry Group |
| Awards / Recognition |
|---|
| Scholarships,fellowships, and awards: American Chemical Society Herman Skolnik award for outstanding contributions to and achievements in the theory and practice of chemical information science and related disciplines. CRC for Polymers Chairman’s Award for Excellence in Commercialization for myelofibrosis drug Royal Academy of Engineering, Distinguished Fellowship (UK) Fellow, Asian Federation for Medicinal Chemistry Senior Scientists CSIRO Service from Science Award for successful technology transfer to the BioRad Corporation CSIRO SAP Award for Business Excellence CSIRO “One-CSIRO” Award for multidisciplinary research CSIRO Medal for Business Excellence for the research Alliance with Schering Plough Animal Health CSIRO SAP Award for Business Excellence DIST Travelling Fellowship (Prof. Graham Richards, Oxford University). Fellow, Royal Australian Chemical Institute Australian Academy of Science /Academia Sinica Fellowship Australian Academy of Science/JSPS Fellowship (Prof. Toshio, Fujita, Kyoto University) General Motors Holden Postgraduate Fellowship Commonwealth Postgraduate Research Award Victorian Government Science Cadetship Commonwealth University Scholarship |
| Publications and Patents Summary |
|---|
| Published over 200 papers, book chapters and patents Reviewers for: Nature Communications Nature Nanotechnology Nature Scientific Reports Chemical Communications Australian Journal of Chemistry Journal of the American Chemical Society Journal of Chemical Information and Modelling Journal of Medicinal Chemistry Journal of Peptide Science Internet Journal of Chemistry Journal of Computational Chemistry Australian Research Council National Health & Medical Research Council NH&MRC Career Development Fellowship panel (2013-) Molecular Informatics CRC Press Journal of Agricultural and Food Chemistry Journal of Molecular Graphics and Modelling Current Pharmaceutical Design Bioorganic and Medicinal Chemistry Letters Journal of Pharmacy and Pharmacology Central European Journal of Chemistry ChemMedChem Angewandte Chemie BioTechniques Artificial Life Chemical Engineering Science Expert Opinion on Drug Discovery The Open Informatics Journal Computer Methods and Programs in Biomedicine Selection panel for IUPAC Richter Prize–Medicinal Chemistry Selection Panel for Jacques Dubois CSA Trust Prize Selection panel for Hope Foundation (Nobel Prize mentoring of ECRs) Selection Panel for Lindau Fellowships (Nobel Prize mentoring of ECRs) More available upon request. |
Language Skills
| Language | Proficiency |
|---|---|
| French | Basic proficiency |
Fields of Expertise
complexity science, computational chemistry, computer-aided molecular design, molecular modeling, peptide mimetic, quantitative structure-activity relationship, quantitative structure-property relationship, nanobiotechnology, hematopoietic stem cell mobilization, nanoparticle, stem cell, pharmaceutical design, nanotechnology, molecular mechanics, cytokine, quantum mechanics