Intellex Acquires Expert by Big Village

We're thrilled to announce that Intellex has acquired Expert by Big Village, effective March 22, 2024. This strategic move enhances our capabilities and strengthens our commitment to delivering exceptional solutions to our customers.

Stay tuned for more updates on how this acquisition will benefit our clients and experts.

For inquiries or more information, please contact us at info@intellex.com.

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Expert Details

Membrane Traffic

ID: 107807 Texas, USA

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MEMBRANE TRAFFIC. All of Expert's work in the last ten years has involved membrane traffic, ranging from genetic analysis of endocytosis and secretion in mammalian cells to biochemical analysis of the entry of protein toxins, including immunotoxins, into cells.

HYBRID TOXINS; IMMUNOTOXINS. The goal of Expert's work with protein toxins is the construction of more potent and specific hybrid immunotoxins that may have chemotherapeutic value. He and his colleagues have applied to patent an approach in this area using toxins based on Pseudomonas aeruginosa exotoxin A.

ENDOCYTOSIS. Expert has done extensive work on the endocytosis of protein toxins and on the endocytosis of transferrin and the transferrin receptor. He has also worked a great deal on mammalian cells expressing genetic defects in the endocytic pathway.

SECRETION. Over the last four years, Expert has studied secretion as it relates to mutants he has isolated that are defective in the secretory pathway.

PSEUDOMONAS AERUGINOSA EXOTOXIN A. For the last five years, Expert has been studying the molecular and cellular biology of the Pseudomonas aeruginosa extoxin A, especially ways to improve immunotoxins made with exotoxin A. He and his colleagues submitted a patent application covering some of this work.

DIPHTHERIA TOXIN. Although the diphtheria toxin is not currently his focus, Expert has had a lot of experience with this toxin in the past and continues to follow the literature in the field.


Education

Year Degree Subject Institution
Year: 1974 Degree: PhD Subject: Biological Chemistry Institution: UCLA
Year: 1968 Degree: BA Subject: Chemistry Institution: University of Washington - Seattle

Work History

Years Employer Title Department
Years: 1980 to 2000 Employer: UNIVERSITY OF TEXAS - DALLAS Title: PROFESSOR OF BIOLOGY Department:
Responsibilities:
Available upon request.
Years Employer Title Department
Years: 1974 to 1980 Employer: Title: Various postdoctoral fellowships Department:
Responsibilities:
Available upon request.

Career Accomplishments

Associations / Societies
Expert is a member of the American Society of Cell Biology and the American Association for the Advancement of Science.
Publications and Patents Summary
Expert has over thirty published research articles and reviews in his fields of expertise.

Fields of Expertise

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