Expert Details
Medicinal Chemistry, Synthetic Organic Chemistry, Drug Discovery, Pharmacokinetics
ID: 730214
Wisconsin, USA
Expert is assiduous researcher. His knowledge of organic synthesis (both conceptual and empirical) is exemplary and is well represented through his research work. His acumen to organic synthesis is well represented through his research on stereoselective synthesis of optically active alpha-amino acids which was successfully accomplished.
Expert is creative and motivated researcher. His cutting edge approach, optimism and perseverance have been the cornerstone of success. We had several beneficial interactions on our research projects. His amiable nature makes him a very pleasing coworker.
He has accumulated sound knowledge and experience in various areas of organic chemistry such as total synthesis, medicinal chemistry, asymmetric synthesis/catalysis, pharmacokinetics, and organoborane chemistry.”
Education
| Year | Degree | Subject | Institution |
|---|---|---|---|
| Year: 2004 | Degree: PhD | Subject: Organic Chemistry | Institution: Indian Institute of Chemical Technology |
| Year: 1997 | Degree: MS | Subject: Chemistry | Institution: Kakatiya University |
| Year: 1995 | Degree: BS | Subject: Chemistry, Botany, Zoology | Institution: Kakatiya University |
Work History
| Years | Employer | Title | Department |
|---|---|---|---|
| Years: 2011 to Present | Employer: Undisclosed | Title: Acting Instructor of Chemistry | Department: Department of Chemistry |
Responsibilities:Available upon request. |
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| Years | Employer | Title | Department |
| Years: 2007 to 2010 | Employer: University of Washington | Title: Research Associate | Department: Department of Chemistry |
Responsibilities:Available upon request. |
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| Years | Employer | Title | Department |
| Years: 2004 to 2006 | Employer: Purdue University | Title: Research Associate | Department: Department of Chemistry |
Responsibilities:Available upon request. |
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International Experience
| Years | Country / Region | Summary |
|---|---|---|
| Years: 2004 to 2006 | Country / Region: United States | Summary: Expert worked as a research associate at the department of chemistry in Purdue University. |
| Years: 2007 to 2011 | Country / Region: United States | Summary: Expert worked as a research associate at the department of chemistry in Employer. |
Career Accomplishments
| Associations / Societies |
|---|
| American Chemical Society; American Chemical Society-Fluorine Division; Drug Discovery News; The Pacific Northwest Mass Spectrometry Group |
| Awards / Recognition |
|---|
| • Awarded a highly competitive research fellowship (Junior Research Fellowship) after qualifying National Eligibility Test (NET) conducted by Council of Scientific and Industrial Research (CSIR), Government of India. Qualified for lectureship in colleges and universities. • Qualified Council of Scientific and Industrial Research (CSIR), Senior Research Fellowship. • Dr. K. V. Rao Scientific Society for Promotion of Science, India; Young Scientist Research Award-2003. • Best Performance/Publication Award (2002) by Indian Institute of Chemical Technology (IICT) on Council of Scientific and Industrial Research (CSIR) foundation day for the paper in Angew. Chem. Int. Ed. (2001). • Best Performance/Publication Award (2003) by Indian Institute of Chemical Technology (IICT) on Council of Scientific and Industrial Research (CSIR) foundation day for the paper in J. Am. Chem. Soc. (2002). |
| Publications and Patents Summary |
|---|
| Expert published several papers in peer-reviewed international journals including Journal of the American Chemical Society, Angew. Chem, Journal of organic Chemistry. etc. and filed 24 international patents (US, World, UK, European, Japan. etc.). |
Additional Experience
| Expert Witness Experience |
|---|
| Expert is experienced in handling air-sensitive reagents/reactions, separation of compounds by flash column chromatography, structure elucidation of organic/organometallic compounds by UV, IR, NMR & Mass spectroscopy. Expert performed key synthetic reactions like Brown’s allylation and crotylation, Suzuki-Miyaura, Negishi coupling, Sharpless dihydroxylation, Heck-, Stille- and Sonogashira coupling reactions. Expert synthesized alkyllithium/alkylmagnesium, organo-zinc, organo-copper and organo-boron reagents. Expert is conversant with modern separation techniques (GC and HPLC), search databases (Scifinder, Beilstein etc.). Instruments operated: GC, HPLC, NMR, IR, UV, polarimeter, Mass, LC-MS/MS etc. |
| Training / Seminars |
|---|
| Expert trained graduate and undergraduate students both in conceptual and experimental organic chemistry. |
| Marketing Experience |
|---|
| Expert developed and synthesized milligram to multigram quantities of several complex intermediates of the typical calcium antagonist “(+)-Diltiazem” via transition metal catalyzed multistep stereoselective organic transformations, and the technology has been transferred to SMS pharmaceuticals Ltd, INDIA Expert also developed short and practical method for the synthesis of Taxol side chain, which is proved to be essential for the biological activity of Taxol, and the technology was transferred to SMS pharmaceuticals Ltd, INDIA |
Language Skills
| Language | Proficiency |
|---|---|
| HINDI | |
| TELUGU |
Fields of Expertise
boron chemistry, chiral chromatography, drug blood level determination, drug discovery, organic synthesis, pharmacokinetics, enantioselective heterogeneous catalysis, organoborane, analytical method optimization, active pharmaceutical ingredient, high-throughput screening (drug discovery), chiral synthesis, chiral separation, phase-transfer catalysis, synthetic crude, heterocyclic compound synthesis, aromatic compound synthesis, amino acid methyl ester, amino acid ester, rational drug design, boron analysis, aromatic diamine, pharmaceutical research and development, enzyme inhibitor, sodium fluoroborate, boron trichloride, aromatic ester, prodrug, peptide coupling, organic compound manufacturing, drug metabolite, pharmaceutical product development, boron hydride chemistry, hydride chemistry, boron trifluoride, supported palladium catalyst, supported metal catalyst, catalyst poison, medicinal chemistry, chiral high-performance liquid chromatography, fine organic synthesis, catalyst regeneration, homogeneous transition metal catalysis, heterogeneous transition metal catalysis, transition metal catalysis, transition metal catalyst, enantioselective catalysis, aromatic compound nitration, aromatic compound catalytic hydrogenation, chirality, pharmaceutical design, enzyme activity assay, transition-metal-mediated organic reaction, asymmetric synthesis, palladium recovery, catalyst recycling, drug development, palladium compound, catalyst mechanism, aromatic isocyanate, chemical process inhibitor, palladium homogeneous catalysis, palladium catalysis, palladium catalyst, heterocyclic chemistry, organopalladium chemistry, synthesis, chemical reaction, alkylation, inorganic catalysis reagent, boron compound, enzyme mechanism, synthesis chemistry, Friedel-Crafts reaction, molecular chirality, chemical reaction mechanism, chemical synthesis, aromatic compound, chemical compound, surface chemistry, quantitative structure-activity relationship, pharmaceutical chemistry, organometallic compound, organometallic chemistry, organic chemistry, inorganic synthesis, inorganic chemistry, homogeneous catalysis, heterogeneous catalysis, chemistry, catalytic hydrogenation, catalyst, catalysis reagent, catalysis, bulk pharmaceutical chemical manufacturing, boric acid, asymmetric induction, aromatic hydrocarbon, aromatic amine, aromatic aldehyde, aromatic alcohol, aromatic acid