Expert Details
Fermentation Development, Optimization, and Production of Recombinant Proteins
ID: 729523
Delaware, USA
Experience in aerobic and anaerobic fermentation and working with various microorganisms including bacteria,
yeast and fungi. Fermentation optimization to improve yield and productivity for production of pharmaceutical
proteins, enzymes, fine chemicals and bio fuels. This was accomplished by media optimization, process
conditions, and fed batch operation. Experience in extractive fermentation as a way to ferment immiscible and
toxic substrates or products.
Scale up and technology transfer:
Projects include cellulase production by fungi, production of recombinant proteins and enzmes and production of
bacterial cellulose by recombinant bacteria. Technology transfer between various groups in US and abroad..
Biotechnology:
Familiar with various aspects of genetic engineering tools and possibilities, down stream processing and process
economics and work closely with experts that represent these disciplines.
Biotransformation to produce fine chemicals using immobilized cells and enzymes.
Scale up of cellulase production by fungi.Scale up of new chemical by recombinant bacteria.
Education
| Year | Degree | Subject | Institution |
|---|---|---|---|
| Year: 1978 | Degree: PhD | Subject: Microbiology and Fermentation | Institution: The Hebrew University of Jerusalem, School of Applied Science |
| Year: 1971 | Degree: MSc | Subject: Applied Microbiology | Institution: The Hebrew University of Jerusalem |
| Year: 1969 | Degree: BSc | Subject: Biochemistry and Microbiology | Institution: The Hebrew University of Jerusalem |
Work History
| Years | Employer | Title | Department |
|---|---|---|---|
| Years: 1994 to Present | Employer: Undisclosed | Title: Associate Scientist | Department: Undisclosed |
Responsibilities:Principal scientist and project leader |
|||
| Years | Employer | Title | Department |
| Years: 1992 to 1994 | Employer: Undisclosed | Title: Chief Microbiologist | Department: Undisclosed |
Responsibilities:Technology transfer and scale up of fermentation process. |
|||
| Years | Employer | Title | Department |
| Years: 1991 to 1992 | Employer: Undisclosed | Title: Research Director | Department: Undisclosed |
Responsibilities:Managed microbiology lab and direct R&D research for bioconversion and biofuel production. |
|||
| Years | Employer | Title | Department |
| Years: 1980 to 1991 | Employer: Undisclosed | Title: Senior Scientist | Department: Undisclosed |
Responsibilities:Scale up and optimization of fermentation processes.Manage project. |
|||
| Years | Employer | Title | Department |
| Years: 1978 to 1980 | Employer: Undisclosed | Title: Post Doctorate | Department: Undisclosed |
Responsibilities:Identification and characterization of thermophilic anaerobic bacteria and fermentation studies. |
|||
International Experience
| Years | Country / Region | Summary |
|---|---|---|
| Years: to Present | Country / Region: Moscow, Russia | Summary: Technology transfer for cellulase production. |
| Years: to Present | Country / Region: Switzerland | Summary: Technology transfer and scale up of cellulase production |
Career Accomplishments
| Associations / Societies |
|---|
| ASM; ACS. |
| Publications and Patents Summary |
|---|
| Ten certified and maintained US patents. More than 30 peer review publications. |
Language Skills
| Language | Proficiency |
|---|---|
| Hebrew | Highly proficient. |
Fields of Expertise
biological process, biotechnology, enzyme, protein, recombinant protein expression, bacterial culture, bacterial fermentation, E. coli, Escherichia coli fermentation, fermentation technology, industrial enzyme, industrial microbiology, industrial process, microbiological broth, gene expression, fermentation, recombinant protein, scale-up, biotransformation, saccharomycete, bacterial contamination, biocatalysis, fermentative ethanol production, yeast extract, ethanol fuel production, yeast fermentation, full-scale test, volatile organic compound, amino acid, sparging, industrial fermentation, applied microbiology, anaerobic microbiological process