Toxicology, Environmental Medicine, Biochemistry, Cancer Causation, DNA Damage & Repair, Genetics, Arsenic, Metals
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Expert has published about 120 articles, mostly on metal carcinogenesis and environmental toxicology, with an emphasis on arsenic. She was first to report on the comutagenicity of arsenic and later developed the only animal model of arsenic-induced skin cancer. She established that arsenic compounds affect the genetic mutation process in unconventional ways, such as inhibition of DNA repair. She participated in the International Agency for Research in Cancer (IARC) review of the carcinogenicity of metals, Lyon, France, 19XX and again in 20XX. Expert organized and chaired the session on mechanisms of carcinogenesis at the NIH/EPA meeting “Arsenic: Health Effects, Mechanisms of Action, and Research Issues”. She was co-organizer of the First, Second, and Third International Meetings on Molecular Mechanisms of Metal Toxicity and Carcinogenicity. In 20XX, Expert edited a Special Issue of Mutation Research devoted to Metals and Carcinogenesis. She was a member of the Scientific Advisory Board (arsenic) for the USEPA. She has been a consultant and expert witness for the legal profession.
In other research, Expert studied the toxicology of environmental agents such as ultraviolet light, chromium, nickel, and other metals. Expert has been an expert witness in food contamination.
Expert has served on a number of Federal Committees to determine risk and mechanism of toxicity of a number of toxicants. She has also consulted for industry and for the legal profession on issues of toxicology. Expert has served on the Chemical Pathology Study Section (NIH), the National Toxicology Program Study Section, the American Cancer Society Study Section (Genetics), twice on the Environmental Health Sciences Review Committee (NIEHS), on NIH Small Business Grants (Genetics) study section, and on the Metabolic Pathology Study Section (NIH). She served on the editorial boards of Environmental and Molecular Mutagenesis, Mutation Research, Molecular Toxicology, and Teratogenesis, Carcinogenesis and Mutagenesis, and is a reviewer for many other journals as well as Federal documents.
She wrote background papers on the role of arsenic compounds in human disease (risk assessments) for a class action lawsuit involving environmental arsenic exposure. In this case, she worked for the defense, and was able to show that the various diseases listed by plaintiffs were not associated with arsenic exposure, but had other causes.For the plaintiff in a case of food contamination causing chemical burn to the mouth, she developed a PowerPoint presentation showing that, contrary to defense's position, there was a very substantial level of contaminant that was enough to cause the burn.She analyzed whether a particular exposure scenario might have contributed to the lung disease in a plaintiff who, it was claimed, had an immune deficiency. She showed that, in fact, the alleged immune deficiency had not been proved.She advised on a case of childhood exposure to a contaminated playground, and examined data of the chemicals found. Among these chemicals were three that had a causal link to the disease in the plaintiff. (Still ongoing).She arranged to have an attorneys office tested for x-ray leakage from a chemotherapy office downstairs. The results showed that there was no leakage.