Expert Details
Molecular Biology, Genetics, Cancer Biology, Radiation Biology, Genetic Engineering
ID: 731251
Colorado, USA
He consulted with a law firm in Washington, DC on a biotechnology patent law dispute; with a South Carolina law firm on an oncology malpractice suit; and with a Canadian law firm on a low-dose radiation exposure suit. He has served as Science Advisory Board member, KromaTid, Inc. KromaTid is a start up biotechnology firm that manufactures molecular cytogenetic and custom gene tracking assays to discover, detect and diagnose the widest range of disease causing mutations – including DNA sequence inversions and translocations – in a single test. Based on Directional Genomic Hybridization™ (dGH), KromaTiD assays generate sequence, location and orientation data from single cells, making them ideal for mixed cell population studies. He has served as member of Scientific Advisory Boards for Employer, University of Texas Medical Branch NASA Specialized Center of Research program, Emory University, and Yale University.
Education
Year | Degree | Subject | Institution |
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Year: 1983 | Degree: PhD | Subject: Biochemistry | Institution: University of Colorado, Boulder |
Year: 1978 | Degree: BA | Subject: Biochemistry | Institution: University of California Santa Barbara |
Work History
Years | Employer | Title | Department |
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Years: 2008 to Present | Employer: Undisclosed | Title: Professor (former Department Head) | Department: Environmental and Radiological Health Sciences |
Responsibilities:For 11 years (2008-2019) managed a diverse faculty with 40-42 members in six sections (Radiation Cancer Biology, Veterinary Radiation Oncology, Veterinary Radiology, Radiation Protection and Measurement/Health Physics, Toxicology, Environmental Health Epidemiology, Industrial Hygiene), overseeing clinical radiology and radiation oncology programs, bachelors, masters, and doctoral degree programs. Expert directed an NIH-funded research lab with 6-8 members from 1990-2018, and his lab is currently funded by the American Lung Association (2020-2022). |
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Years | Employer | Title | Department |
Years: 1996 to 2008 | Employer: University of New Mexico School of Medicine | Title: Assoc Professor/Professor/Chair | Department: Department of Molecular Genetics and Microbiology |
Responsibilities:Directed NIH-funded research lab focused on DNA repair and cancer biology, and for 8 years Chaired the Department of Molecular Genetics and Microbiology with 17-18 faculty focused on research in infectious disease, virology, cell biology and cancer biology. Also led/co-led the Cancer Biology section of the NCI-designated UNM Cancer Center. |
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Years | Employer | Title | Department |
Years: 1990 to 1996 | Employer: Harvard University School of Public Health | Title: Assistant/Associate Professor | Department: Cancer Biology (Radiation Biology section) |
Responsibilities:Directed NIH-funded research lab |
Government Experience
Years | Agency | Role | Description |
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Years: 1993 to Present | Agency: NIH | Role: Study section member (full member or ad hoc member) | Description: He is responsible for reviewing R01 and P01 grant applications for the National Cancer Institute and the National Institute of General Medical Sciences |
Years: 1987 to 1990 | Agency: Los Alamos National Laboratory | Role: Postdoctoral fellow | Description: He performed molecular genetic and radiobiology research focused on DNA repair mechanisms and cancer. |
International Experience
Years | Country / Region | Summary |
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Years: 2008 to 2018 | Country / Region: Japan | Summary: He led an effort to link basic scientists, translational scientists, veterinarians, and physicians at Employer, the University of Colorado School of Medicine, and the Japan National Institute of Radiological Sciences. Another goal of this project was to construct a novel cancer research and treatment facility in Colorado, in collaboration with the NIRS, focused on carbon and other heavy ion radiation therapy. Related projects include the development of joint US-Japan graduate training programs in radiobiology, medical physics, and radiation oncology, and a program to transfer US cancer patients to Japan for carbon ion radiotherapy at the NIRS facility. He organized an international conference focused on radiation biology and radiation oncology (photon, proton, carbon ions) in 2010, 2012, 2013, and 2014. |
Years: 2013 to 2019 | Country / Region: Mexico | Summary: He led a team of environmental health scientists from Employer in the development of projects in Todos Santos, Baja California Sur, Mexico. Projects under consideration include efficient waste disposal/waste-to-energy generation, water use and water safety, and agricultural safety (pesticides, etc). |
Years: 2005 to Present | Country / Region: Canada, Ireland, Netherlands, Israel, UK, Italy | Summary: Served as grant reviewer and program review for national funding agencies in Canada, Ireland, Netherlands, Israel, UK, and Italy. Most of these were mail-review, but served as chair of site visit program review team evaluating the Genome Stability group at the University of Galway, Ireland in 2005, 2009, and 2013 for Science Foundation Ireland. |
Career Accomplishments
Associations / Societies |
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Genetics Society of America (1991-present), American Association for Cancer Research (1998-2010), Radiation Research Society (1994-present) |
Professional Appointments |
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Associate Editor, Genetics (2010-present), Associate Editor, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis (2019-present), Associate Editor, Molecular Biotechnology (1993-2016), Editorial Board (founding member), Nucleic Acids Research Cancer (2019-present), Editorial Board, ISRN Genetics (2012-2014), Editorial Board, Biotechniques (1996-2006) |
Awards / Recognition |
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Endowed Chair, UNM School of Medicine, 2008 (declined, relocated to Employer) Distinguished Foreign Scientist, Japan National Institute of Radiological Science (2011-2018) Exceptional Mentor Award, Jack and June Richardson Honors Thesis program (2013) Diploma of Excellence, Gheorghe Asachi Technical University of Iaşi, Romania (2018) |
Publications and Patents Summary |
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Published more than 120 original articles, more than 20 review articles in DNA repair, cell biology and cancer biology fields, has one patent, edited or co-edited 6 volumes (3 on DNA damage and repair, 3 technical manuals). |
Additional Experience
Expert Witness Experience |
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Expert witness/provided deposition in biotechnology patent case (gene therapy) for law firm in Washington, DC. Expert provided testimony in oncology malpractice suit in South Carolina. Expert provided testimony in low-dose radiation exposure suit in Toronto, Canada. |
Training / Seminars |
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Presented 88 invited seminars at universities and professional meetings, organized four international symposia focused on radiation oncology (basic and translational science, and clinical practice). Organized sessions at 6 international scientific conferences. |
Vendor Selection |
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Directed NIH funded research laboratory typically funded by 2-3 R01 grants. Led basic science department at Univ of New Mexico School of Medicine: $6M annual budget. Led 40+ faculty member department with basic, applied, and clinical (veterinary) sections: $13M annual budget. |
Marketing Experience |
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Lead on patent licensed by 3 biotechnology companies. Developed research collaborations with biotech/pharmaceutical industry partners. Developed a program with Japan National Institute of Radiological Sciences to transfer US cancer patients for novel radiotherapy in Japan - this project also involves Japanese insurance industry partners and partners at the University of Colorado Health Systems (University of Colorado School of Medicine and Poudre Valley Health System in Fort Collins, CO). |
Other Relevant Experience |
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30+ years of teaching experience in molecular genetics, cancer biology, biotechnology. Broad knowledge base due to PhD in plant genetics, postdoctoral experience in yeast molecular genetics and mammalian cell molecular genetics, and experience on the the faculty at Harvard University (7 years), UNM School of Medicine (12 years, 8 as department chair), and Employer College of Veterinary Medicine and Biomedical Sciences (14 years, 11 years as department head). Directed/co-Directed Cancer Biology program for NCI-designated Cancer Center (UNM) and currently a member of University of Colorado Cancer Center, and CSU Flint Animal Cancer Center. |
Fields of Expertise
cancer biology, cancer chemotherapeutic agent, cloning technique, genetic engineering, ionizing radiation, molecular biology, molecular genetics, radiobiology, cancer research, oxidative stress, antineoplastic antimetabolite, DNA fingerprinting, eukaryotic gene, SDS-PAGE, chromosome paint, fluorescence in situ hybridization probe, free radical, colon cancer, cisplatin, oncogene, electroporation, cancer chemotherapy, radiation oncology, mitosis, molecular genetics testing, protein modification, protein biochemistry, molecular oncology, molecular cytogenetics, DNA technology, applied molecular biology, nucleic acid enzymology, sarcoma, immunocytochemistry, biochemical research, immunohistochemistry, gene expression regulation, cancer, cancerous tumor, DNA sequencing, radiation therapy, DNA structure, cell (biology), DNA, protein, radon, oncology, oncogenesis, leukemia, genetics, genetic manipulation, chromosome, carcinogen, biochemistry