Intellex Acquires Expert by Big Village

We're thrilled to announce that Intellex has acquired Expert by Big Village, effective March 22, 2024. This strategic move enhances our capabilities and strengthens our commitment to delivering exceptional solutions to our customers.

Stay tuned for more updates on how this acquisition will benefit our clients and experts.

For inquiries or more information, please contact us at info@intellex.com.

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Expert Details

Structural Based Drug Design, Docking and MD Simulations, Chemoinformatics and Bioinformatics

ID: 725675 California, USA

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Expert has extensive experience in designing small molecule drugs for oncology targets such as kinases. He can help you narrow down the number of compounds you are going search for a new drug by an efficient computational algorithm. He can model the binding mode of your compounds. He has design modifications of your lead for optimization. He develops tools which is useful for you to navigate your compound structures, activities and other associated data.

He has extensive experience in small molecule drug discovery.

He consulted on Ligand-protein binding mode analysis for a drug discovery company located in South San Francisco. He has references available upon request.

Education

Year Degree Subject Institution
Year: 1999 Degree: PhD Subject: Molecular and computatinal Biology Institution: University of California at Berkeley

Work History

Years Employer Title Department
Years: 2001 to 2008 Employer: Plexxikon Inc Title: Sr. Scientist Department: Informatics
Responsibilities:
He routinely applied computational chemistry methods to support drug discovery, optimization, and development in medicinal chemistry project team settings. He made significant contributions to multiple projects which led to clinical compounds, favorable licensing or financing deals. He was a key player of Plexxikon’s BRaf team which discovered a specific BRaf V600E mutant inhibitor, PLX4032, which now is in Phase I clinical trial. Hiss research has resulted in multiple publications and several U.S. patents and patent applications. He led an interdisciplinary team of chemists, crystallographer, molecular biologists and assay biologists to discover small molecule drugs to combat cancer.

Additional Experience

Expert Witness Experience
He has 8 years of experience in structure-based drug design, cheminformatics, and scientific programming. Skills includes docking, molecular dynamics simulations, data management and multiple variable analysis. ADMET prediction, data classification.
Marketing Experience
Small molecule drug discovery and design. Kinase. Renin.
Other Relevant Experience
Chemmoinformatics and cooperate data management infrastructure.

Language Skills

Language Proficiency
Chinese My native language is Chinese

Fields of Expertise

antitumor drug, drug, medicinal herb, new drug, database management system, pharmacology, pharmacokinetics, molecular biology, data analysis

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