Expert Details

Platelets, Megakaryocytes, Calcium Signalling, Ion Channels

ID: 729035 United Kingdom

Expert Smith has 20+ years of experience in cell signalling and functional assays of platelet activation. He has edited 3 major books on techniques to study platelets and their precursor cells, and has a patent for development of novel anti-thrombotics. He is also an expert in studies of calcium signalling, ion channels and G-protein-coupled receptors. He has a PhD in Physiology, 20+ years of University teaching and examining, including at Cambridge. He has published more than 65 papers on cell signalling and cellular activations, particularly in blood platelets.

He has spoken on the general topic of "Calcium signalling" at International conferences arranged by 1. a major company developing new machines to study ionic signalling in living cells 2. a European University as part of an advanced skills class to study cellular signalling .He has assayed a cell line developed by a Biotech company with the aim of identifying a novel (orphan) ion channel.He has beta-tested software developed by major microscope manufacturers for the measurement of intracellular calcium.

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Education

Year	Degree	Subject	Institution
Year: 1986	Degree: PhD	Subject: Cell Signalling, Physiology	Institution: University of Bristol
Year: 1983	Degree: BSc	Subject: Physiology	Institution: University of Sheffield

Work History

Years	Employer	Title	Department
Years: 2007 to Present	Employer: Undisclosed	Title: Professor of Cellular Physiology	Department:
Responsibilities: Expert Smith is in charge of a research laboratory focusing on novel aspects of cell signalling in platelets and other cells, particularly the role of ion channels and calcium signals. He teaches and examines in several areas of Physiology.
Years	Employer	Title	Department
Years: 1989 to 2007	Employer: University of Cambridge	Title: University Lecturer	Department:
Responsibilities: Expert Smith was in charge of a research laboratory focusing on novel aspects of cell signalling in platelets and other cells, particularly the role of ion channels and calcium signals. He taught and examined in several areas of Physiology.

Government Experience

Years	Agency	Role	Description
Years: 2004 to 2005	Agency: Medical Research Council	Role: Advisory Board, Cell & Molecular Medicine	Description: Advisor to the Medical Research Council grant awarding body

Career Accomplishments

Associations / Societies
Physiological Society

Professional Appointments
Member of the Editorial board of Thrombosis & Haemostasis and Frontiers in Membrane Physiology and Biophysics

Publications and Patents Summary
Has more than 65 publications and has edited 3 books, focusing on cell signalling in platelet and megakaryocytes.

Additional Experience

Expert Witness Experience
Consulting on various aspects of techniques to study calcium signals and platelet activation.

Training / Seminars
Seminars and practicals on patch clamp and calcium measurements. Invited lectures on these topics both nationally and internationally

Vendor Selection
He has interacted with multiple companies in the course of establishing a laboratory that is focused on calcium measurements and electrophysiology

Marketing Experience
On-going cutting edge research in cell signalling provides information on needs for next generation technology to study ion channels and calcium signalling.

Fields of Expertise

blood platelet, calcium channel, platelet aggregation, cell membrane