Expert Details
Clinical Chemistry, Laboratory Diagnostics, Immunoassay Development, Therapeutic Drug Monitoring
ID: 722043
New York, USA
Expert has synthesized several dye polymers, conjugated them to analytes like thyroxine, to develop a thyroxine immunoassay. He has so far developed homogeneous or heterogeneous immunoassays, using colorimetric, enzyme, or chemiluminescent labels, and many types of paramagnetic, or otherwise 'beads' for some twenty analytes in clinical diagnostics, including drugs that need therapeutic monitoring. He has many publications in the field and is frequently invited to give seminars in national and international conferences.
Expert has developed commercially sold methods for therapeutic drug monitoring of several cardioactive, antiasthmatic, antiepileptic and antibiotic drugs. He has written some 20 papers, presented more than 30 posters, and given seminars in many national and international conferences on therapeutic drug monitoring in human, drug toxicology and drug-drug interaction.
Expert was a consultant to a company's deoxypyridinoline assay development, when the team faced serious technical issues. He developed methods and assisted the team to investigate why the new assay sometimes gave incorrect clinical results, and showed how it could be fixed.He was asked to consult and assist to company's ACS:180® (Automated Chemiluminescence System) vancomycine assay product. He developed a new way to conjugate the chemiluminescent label to the analyte. The new process reduced process time by 60% and cost by 78%, and made the process more reliable.
Education
Year | Degree | Subject | Institution |
---|---|---|---|
Year: 1983 | Degree: Ph.D. | Subject: Bio-Organic Chemistry | Institution: Yale University |
Year: 1978 | Degree: M.Phil. | Subject: Biochemistry | Institution: Yale University |
Year: 1977 | Degree: M.S. | Subject: Biochemistry | Institution: Yale University |
Year: 1975 | Degree: M.S. | Subject: Organic Chemistry | Institution: Indian Institute of Technology |
Year: 1973 | Degree: B.S. | Subject: Chemistry | Institution: Calcutta University |
Work History
Years | Employer | Title | Department |
---|---|---|---|
Years: 1992 to Present | Employer: Undisclosed | Title: Manager, Assay Development | Department: Diagnostics |
Responsibilities:Expert is manager of (Undisclosed)'s assay development for their automated chemiluminescent immunoassay systems. |
|||
Years | Employer | Title | Department |
Years: 1989 to 1992 | Employer: Cirrus Diagnostics | Title: Senior Scientist | Department: |
Responsibilities:Expert was engaged in the development of and regulatory filing for immunoassays for the automated IMMULITE analyzer. |
|||
Years | Employer | Title | Department |
Years: 1984 to 1989 | Employer: Photest Diagnostics | Title: Scientist | Department: |
Responsibilities:He researched the synthesis and conjugation of chromogenic polymers to biomolecules, and also worked on immunoassay development. |
|||
Years | Employer | Title | Department |
Years: 1983 to 1984 | Employer: University of Texas | Title: Postdoctoral Fellow | Department: Department of Pathology |
Responsibilities:Expert’s postdoc work at the Univ. of Texas consisted of research in clinical diagnostics. Additionally, he acted as Assistant Director of Clinical Chemistry. |
Career Accomplishments
Associations / Societies |
---|
Expert is a member of the American Association of Clinical Chemistry (AACC), the International Federation of Clinical Chemistry, the International Association of Therapeutic Drug Monitoring, and the Clinical Ligand Assay Society (CLAS). |
Licenses / Certifications |
---|
He has the distinction of receiving the highest certification in clinical chemistry – Expert is a certified Diplomate from the American Board of Clinical Chemistry (ABCC) in Washington, D.C. |
Professional Appointments |
---|
He is on the Editorial Board for the AACC’s bimonthly Therapeutic Drug Monitoring (Ther Drug Monit), and is an Edit Reviewer for Life Sciences, the Journal of Immunochem. Research, and AACC National Meeting Abstracts. |
Awards / Recognition |
---|
Expert has received numerous awards and merits for his work. He won Best Speaker Award at the AACC National Meeting, San Francisco, and the Clinical Chemistry Recognition Award from the association. He was the recipient of a Quality Recognition Award. During his graduate studies at Yale University, Expert obtained the highest GPA (4.0 equivalent) and a Merit Fellowship from the school. Prior to this, he was National Science Talent Scholar, Government of India, and National Scholar, Government of India (based on top scorer in National Merit Test, Government of India). |
Publications and Patents Summary |
---|
He has 38 papers, 46 abstracts, and four patents in the field of analytical chemistry, clinical chemistry, immunoassay development, and therapeutic drug monitoring-clinical toxicology. |
Additional Experience
Training / Seminars |
---|
Expert has delivered many presentations during his professional career. He presented a workshop on assay interference at the National Meetings of the American Association of Clinical Chemistry. He also presented roundtables on various topics in clinical diagnostics at: the National Meetings of the AACC the International Federation of Clinical Chemistry in Florence, the International Congress of Clinical Chemistry in London, and the International Conference of Therapeutic Drug Monitoring in Vienna. |
Vendor Selection |
---|
He has much experience with HPLC, having set up high performance liquid chromatography systems at his employers. This involved screening and choosing a vendor, arranging set-up and supervising instrument use. |
Language Skills
Language | Proficiency |
---|---|
German | Expert reads and writes German well. The language was a graduate school requirement, used in perusing scientific literature. |
Hindi | He learned Hindi in school in India. |
Bengali | Expert is highly proficient in Bengali, his mother tongue. |
Fields of Expertise
analysis technique, analyte, clinical diagnostics, immunochemistry, protein biochemistry, clinical chemistry, immunoassay, assay development, drug blood level determination, drug toxicology, drug-drug interaction, drug monitoring, therapeutic drug monitoring, medical diagnostic test, drug interaction, assay protocol, activated ester, drug allergy, titration, analytical monitoring, bioanalytical chemistry, metal ion sensor, apoenzyme, radioanalytical chemistry, deionized water quality, analytical test, analytical testing, toxicological hazard, analytical chemistry instrument, sonication, medicinal chemistry, bioprocessing, clinical laboratory, alkaline phosphatase, multiple toxin interaction, clinical toxicology, applied toxicology, bioorganic chemistry, toxic substance, clinical pathology, receptor biochemistry, molecular biochemistry, analytical biochemistry, biochemical research, organic functional group analysis, quantitative chemical analysis, qualitative chemical analysis, analytical reagent, amino acid, toxicology, qualitative biochemistry, protein sequencing, physical biochemistry, organic chemical structure, metabolism, enzymology, clinical trial, chemical analysis, carcinogenicity, biophysics, biomedical sensor, biochemistry, bilirubin, antigen, antibody, analytical chemistry